Journal of Cellular Physiology
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#1Tao Bai (Zhengzhou University)H-Index: 2
#2Ruopeng Liang (Zhengzhou University)H-Index: 1
Last. Yu-Ling Sun (Zhengzhou University)H-Index: 8
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Primary liver cancer is the second most frequent cause of cancer-related deaths. Ferroptosis, a recognized form of regulated cell death, recently gains attention. MicroRNA-214-3p (miR-214) plays a regulatory role in hepatocarcinogenesis. However, the role of miR-214 in cellular ferroptosis is unclear. This study aimed at elucidating whether miR-214 could regulate ferroptosis of liver cancer. In vitro, HepG2 and Hep3B cancer cells were treated with erastin, a ferroptosis inducer, and then erastin...
#1Mounesan Leila (Pasteur Institute of Iran)
#2Sabour Siamak (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 1
#1Anand Joseph (IVRI: Indian Veterinary Research Institute)H-Index: 1
#2Indu Baiju (IVRI: Indian Veterinary Research Institute)H-Index: 2
Last. Gutulla Saikumar (IVRI: Indian Veterinary Research Institute)H-Index: 1
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Mesenchymal stem cells-conditioned media (MSCs-CM) contains several growth factors and cytokines, thus may be used as a better alternative to stem cell therapy, which needs to be elucidated. The present study was conducted to evaluate the therapeutic potential of caprine, canine, and guinea pig bone marrow-derived MSCs-CM in excision wound healing in a guinea pig model. MSCs were obtained from bone marrow, expanded ex vivo and characterized as per ISCT criteria. CM was collected assayed by weste...
2 CitationsSource
#1Zahra PayandehH-Index: 3
#2Saeed KhaliliH-Index: 9
Last. Behzad BaradaranH-Index: 24
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Colorectal cancer (CRC) is still considered as the third most frequent cancer in the world. Microsatellite instability (MSI), inflammation, and microRNAs have been demonstrated as the main contributing factors in CRC. Subtype 1 CRC is defined by NK cells infiltration, induction of Th1 lymphocyte and cytotoxic T cell responses as well as upregulation of immune checkpoint proteins including programmed cell death-1 (PD-1). Based on the diverse features of CRC, such as the stage and localization of ...
2 CitationsSource
#1Rafael A. Casuso (UGR: University of Granada)H-Index: 8
#2Saad Al Fazazi (UGR: University of Granada)H-Index: 1
Last. Jesús R. Huertas (UGR: University of Granada)H-Index: 27
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Training induces a number of healthy effects including a rise in skeletal muscle (SKM) glucose uptake. These adaptations are at least in part due to the reactive oxygen species produced within SKM, which is in agreement with the notion that antioxidant supplementation blunts some training-induced adaptations. Here, we tested whether hydroxytyrosol (HT), the main polyphenol of olive oil, would modify the molecular regulators of glucose uptake when HT is supplemented during exercise. Rats were inc...
#1Yuqi Chen (Soochow University (Suzhou))
#2Feng Zhang (Fudan University)
Last. Xiang Zhou (Soochow University (Suzhou))H-Index: 32
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Hydrogen sulfide (H2 S), which has been identified as the third gaseous signaling molecule after nitric oxide (NO) and carbon monoxide (CO), plays an important role in maintaining homeostasis in the cardiovascular system. Endogenous H2 S is produced mainly by three endogenous enzymes: cystathionine β-synthase, cystathionine γ-lyase, and 3-mercaptopyruvate sulfur transferase. Numerous studies have shown that H2 S has a significant protective role in myocardial ischemia. The mechanisms by which H2...
#1Kwang-Hoon Chun (Gachon University)H-Index: 8
#2Seung-Ju ChoH-Index: 4
Last. Seung Ki Lee (SNU: Seoul National University)H-Index: 32
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Protein kinase C-δ (PKCδ) is a diacylglycerol-dependent, calcium-independent novel PKC isoform that is engaged in various cell signaling pathways, such as cell proliferation, apoptosis, inflammation, and oxidative stress. In this study, we searched for proteins that bind PKCδ using a yeast two-hybrid assay and identified murine arrest-defective 1 (mARD1) as a binding partner. The interaction between PKCδ and mARD1 was confirmed by glutathione S-transferase pull-down and co-immunoprecipitation as...
#1Somayeh Mohammadpour (IAU: Islamic Azad University)
#2Amir Torshizi Esfahani (Islamic Azad University North Tehran Branch)H-Index: 1
Last. Reza Ranjbar (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 21
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The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human populations sparked a global pandemic of the coronavirus disease 2019 (COVID-19). According to preliminary data, about 14% of cases are considered severe and 5% of cases result in critical illness and, reported case fatality rates vary from 1% to more than 7%. However, the symptoms of the disease and the clinical outcome are very different in infected people. In view of these differences, it is clearly app...
#1Cong Zhou (NBU: Ningbo University)
#2Xin Zhao (NBU: Ningbo University)
Last. Shiwei Duan (NBU: Ningbo University)
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MicroRNA (miRNA) is a noncoding single-stranded RNA molecule that can regulate the posttranscriptional expression level of a gene by binding to the 3'-untranslated region (3'-UTR) of the target messenger RNA. miR-543 is a kind of miRNA, which plays an important role in the occurrence and development of various human cancerous and noncancerous diseases. miR-543 directly or indirectly regulates a large number of downstream target genes and plays an important role in cellular components, biological...
#1Guifeng Tan (SYSU: Sun Yat-sen University)
#2Limin Wang (Academy of Medical Sciences, United Kingdom)H-Index: 3
Last. Zhonglin Liu (SYSU: Sun Yat-sen University)H-Index: 7
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Schizophrenia (SZ) is characterized by a high morbidity and disability rate and has gradually increased in rate and caused much burden. However, the pathogenesis of SZ is elusive and may include changes in the biological molecules in exosomes. In this study, we first compared the alterations of plasma exosomal circular RNAs (exo-circRNAs) from SZ patients and matched health controls by high-throughput sequencing. We further explored whether plasma exo-circRNAs can be estimable targets for resear...
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Molecular biology
Cell biology