The role of autophagy in resistance to targeted therapies
Abstract
Autophagy is a self-degradative cellular process, involved in stress response such as starvation, hypoxia, and oxidative stress. This mechanism balances macro-molecule recycling to regulate cell homeostasis. In cancer, autophagy play a role in the development and progression, while several studies describe it as one of the key processes in drug resistance. In the last years, in addition to standard anti-cancer treatments such as chemotherapies...
Paper Details
Title
The role of autophagy in resistance to targeted therapies
Published Date
Aug 1, 2020
Journal
Volume
88
Pages
102043 - 102043
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History