Abstract WP161: Sovateltide Promotes Regeneration and Functional Recovery of Ischemic Brain by Improving Mitochondrial Function

Mitochondrial dysfunction is associated with cerebral ischemic stroke. Sovateltide (IRL-1620; PMZ-1620) undergoing clinical trials (NCT04047563; NCT04046484) has been demonstrated, in preclinical studies, to provide recovery of brain functions when administered following acute cerebral ischemic stroke. We hypothesize that sovateltide preserves mitochondrial activity and provides neural protection and regeneration. We investigated the effect of...