Micrometer-scale light-addressable potentiometric sensor on an optical fiber for biological glucose determination

A novel light-addressable potentiometric sensor (LAPS), on the micrometer scale, is presented for rapid determination of blood and urine glucose. A LAPS chip with <150 μm working diameter is fabricated using standard semiconductor technique, and assembled onto an optical fiber of a laser module to form a micro-sized device. An active circuit design, containing on-board light driver and transimpedance amplifier, is introduced to simplify...