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Analytica Chimica Acta
IF
5.26
Papers
39010
Papers 39275
1 page of 3,928 pages (39.3k results)
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#1Yongjun Zheng (SEU: Southeast University)
#2Deng Pan (SEU: Southeast University)H-Index: 3
Last.Yanfei Shen (SEU: Southeast University)H-Index: 24
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Abstract NAD(P)H: Quinone Oxidoreductase 1 (hNQO1) is a cytosolic flavin two-electron reductase involved in many physiological and pathological processes that is overexpressed in many cancers and recognized as a potential cancer biomarker. However, it is still challenging for highly sensitive and selective monitoring hNQO1 in living cells. Here, we developed a highly selective and ultrasensitive hemicyanine-based near-infrared (NIR) fluorescence probe (probe HCYSN) for the sensing of hNQO1 activ...
#1Lei Meng (JLU: Jilin University)H-Index: 1
Last.Yuqing Wu (JLU: Jilin University)H-Index: 25
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Abstract It is of great importance to detect chlorotetracycline (CTC) in a highly sensitive and specific way because of its wide distribution in aquaculture and animal husbandry. Herein, we propose a novel ratiometric fluorescence strategy to assay CTC by using bovine serum albumin stabilized gold nanoclusters (BSA-AuNCs). The BSA-AuNCs consisting of 25 gold atoms (Au25NCs) display a red emission at 640 nm (λex = 370 nm). In the presence of CTC, a new blue emission at 425 nm is emerged and its i...
#1Carla Santana Santos (USP: University of São Paulo)H-Index: 4
#2Felipe Conzuelo (RUB: Ruhr University Bochum)H-Index: 15
Last.Wolfgang Schuhmann (RUB: Ruhr University Bochum)H-Index: 63
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Abstract The Scanning Bipolar Electrochemical Microscope (SBECM) allows precise positioning of an electrochemical micro-probe serving as bipolar electrode that can be wirelessly interrogated by coupling the electrochemical detection reaction with an electrochemiluminescent reporting process. As a result, the spatially heterogeneous concentrations of an analyte of interest can be converted in real time into a map of sample reactivity. However, this can only be achieved upon optimization of the an...
#1Fangyuan Xu (SNNU: Shaanxi Normal University)H-Index: 1
#2Mengyue Fan (SNNU: Shaanxi Normal University)
Last.Xinrui Duan (SNNU: Shaanxi Normal University)H-Index: 1
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Abstract Genetically encoded fluorescent biosensors are particularly promising sensors to examine biochemical processes in a complex cellular context. RNA mimics of GFP are RNA-fluorophore complexes that emit green fluorescence comparable in brightness to fluorescent proteins. The fluorophore is non-fluorescent until it binds with specific RNA. We designed and developed a dual activated fluorescent probe based on RNA mimics of GFP for the detection of an intracellular nitroreductase. Our probe o...
#1Yuying Wang (Fudan University)
#2Yan Cai (Fudan University)H-Index: 6
Last.Haojie Lu (Fudan University)H-Index: 33
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Abstract N-glycans are involved in a variety of biological processes and associated with many diseases. However, the sensitive and specific detection of glycans via mass spectrometry (MS) remains challenging due to their relatively low abundance and low ionization efficiency. In this work, a new method termed glycan reductive amino acid coded affinity tagging (GRACAT) is developed to address these problems. Through labeling the reducing ends of glycan with a biotinylated arginine, the ionization...
#1Xiaoxia Liu (SWU: Southwest University)
#2Xia Li (SWU: Southwest University)H-Index: 1
Last.Yun Xiang (SWU: Southwest University)H-Index: 36
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Abstract The development of methods that can detect telomerase with high selectivity and sensitivity is critical for early diagnosis and treatment of telomerase-related cancers. In this regard, we describe in this work the establishment of a telomerase-initiated and nicking endonuclease-assisted cascade recycling signal amplification approach for non-label and highly sensitive fluorescent detection of telomerase from cancer cells. The target telomerase triggers the elongation of one strand in a ...
#1Hao-Hua Deng (Fujian Medical University)H-Index: 19
#2Xiang-Yu Fang (Fujian Medical University)
Last.Wei Chen (Fujian Medical University)H-Index: 33
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Abstract Although numerous sensors have been successfully fabricated for the detection of various heavy metal ions by employing fluorescent gold nanoclusters (AuNCs) as nanoprobes, serious cross-interference often occurs when these ions coexist in samples, which results in glaring errors in quantification. In this study, glutathione-protected AuNCs (GSH-AuNCs) were synthesized and found to respond to both Cu2+ and Hg2+ via fluorescence suppression. Intriguingly, addition of Ag+ to GSH-AuNCs coul...
#1Heidi Birch (DTU: Technical University of Denmark)H-Index: 5
#2Aaron D. Redman (ExxonMobil)H-Index: 10
Last.Philipp Mayer (DTU: Technical University of Denmark)H-Index: 39
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Abstract Water solubility is one of the most important and frequently used physical-chemical properties of chemicals. It is crucial within several industrial sectors, in research and in the regulatory sector e.g. for the risk and hazard assessment of chemicals. The most recent OECD guideline (Test No. 105) for measuring solubility is from 1995 and limited to mono-constituent, stable and non-volatile substances. This OECD guideline and the described methods are not suited for several groups of di...
#1Rouxi Zhang (CDUT: Chengdu University of Technology)
#2Juris Meija (National Research Council)H-Index: 24
Last.Lu Yang (National Research Council)H-Index: 29
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ABSTRACT The processes of planetary accretion or formation of the Earth and other celestial objects can be studied by using the 182Hf-182W chronometer which requires precise measurements of tungsten isotope ratios. Many comparative measurements for the isotopic composition of tungsten have been performed using either thermal ionization mass spectrometry (TIMS) or multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS). Yet, calibrated measurements of tungsten isotope ratios, and...
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