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Original paper

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

Volume: 17, Issue: 6, Pages: 613 - 620
Published: Mar 19, 2020
Abstract
The outbreak of Coronavirus Disease 2019 (COVID-19) has posed a serious threat to global public health, calling for the development of safe and effective prophylactics and therapeutics against infection of its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as 2019 novel coronavirus (2019-nCoV). The CoV spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as...
Figures & Tables
paperFigureImage
Fig. 1 Characterization of SARS-CoV-2 RBD. a Multiple sequence alignment of RBDs...
paperFigureImage
Fig. 2 Detection of SARS-CoV-2 RBD binding to human ACE2 receptor. a Flow cytome...
paperFigureImage
Fig. 4 Ability of SARS-CoV-2 RBD to inhibit viral entry, as well as its cross-re...
Paper Details
Title
Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
Published Date
Mar 19, 2020
Volume
17
Issue
6
Pages
613 - 620
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