Original paper
Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes
Abstract
Bulk and single-cell DNA sequencing has enabled reconstructing clonal substructures of somatic tissues from frequency and cooccurrence patterns of somatic variants. However, approaches to characterize phenotypic variations between clones are not established. Here we present cardelino (https://github.com/single-cell-genetics/cardelino), a computational method for inferring the clonal tree configuration and the clone of origin of individual cells...
Paper Details
Title
Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes
Published Date
Mar 16, 2020
Journal
Volume
17
Issue
4
Pages
414 - 421
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Notes
History