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Nature Methods
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Published on 2019in Nature Methods28.47
Guoqiang Li5
Estimated H-index: 5
(Ludwig Institute for Cancer Research),
Yaping Liu (UC: University of Cincinnati)+ 5 AuthorsBing Ren82
Estimated H-index: 82
(UCSD: University of California, San Diego)
We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC reveals coordinated DNA methylation status between distal genomic segments that are in spatial proximity in the nucleus, and delineates heterogeneity of both the chromatin architecture and DNA methylome in a mixed population. It enables simultaneous characterization of cell-type-specific chromatin organization and epigenome in complex tissues.
Published on Oct 1, 2019in Nature Methods28.47
Jimmy Tsz Hang Lee , Martin Hemberg16
Estimated H-index: 16
Published on 2019in Nature Methods28.47
Rita Strack13
Estimated H-index: 13
BODIPY dimerization is exploited for super-resolution imaging and single-particle tracking of lipids in living cells.
Published on 2019in Nature Methods28.47
Arunima Singh4
Estimated H-index: 4
Published on 2019in Nature Methods28.47
Rita Strack13
Estimated H-index: 13
Published on 2019in Nature Methods28.47
Nicole Rusk9
Estimated H-index: 9
Published on Aug 26, 2019in Nature Methods28.47
Lloyd M. Smith62
Estimated H-index: 62
(UW: University of Wisconsin-Madison),
Paul Martin Thomas33
Estimated H-index: 33
(NU: Northwestern University)
+ 18 AuthorsLissa C. Anderson2
Estimated H-index: 2
Published on Oct 1, 2019in Nature Methods28.47
Meghan Driscoll10
Estimated H-index: 10
(UTSW: University of Texas Southwestern Medical Center),
Erik S. Welf14
Estimated H-index: 14
(UTSW: University of Texas Southwestern Medical Center)
+ 4 AuthorsGaudenz Danuser59
Estimated H-index: 59
(UTSW: University of Texas Southwestern Medical Center)
Rapid developments in live-cell three-dimensional (3D) microscopy enable imaging of cell morphology and signaling with unprecedented detail. However, tools to systematically measure and visualize the intricate relationships between intracellular signaling, cytoskeletal organization and downstream cell morphological outputs do not exist. Here, we introduce u-shape3D, a computer graphics and machine-learning pipeline to probe molecular mechanisms underlying 3D cell morphogenesis and to test the in...
Published on 2019in Nature Methods28.47
Arunima Singh4
Estimated H-index: 4
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