CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration
Abstract
RNA-targeting CRISPR system Cas13 offers an efficient approach for manipulating RNA transcripts in vitro. In this perspective, we provide a proof-of-concept demonstration that Cas13-mediated Vegfa knockdown in vivo could prevent the development of laser-induced CNV in mouse model of Age-related macular...
Paper Details
Title
CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration
Published Date
Mar 3, 2020
Journal
Volume
7
Issue
5
Pages
835 - 837
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Notes
History