Original paper
All-Optical Analysis of TRPC3/6 Signalling in Mast Cells
Abstract
Transient receptor potential canonical channels TRPC3/6 are expressed in various cell types of the immune system. These Ca2+ permeable channels are typically activated downstream of the phospholipase C (PLC) pathway, but their role in immune cell Ca2+ handling is still elusive. We set out to explore the impact of TRPC3 and TRPC6 function in RBL mast cells at the level of local, sub-plasmalemmal and global cellular Ca2+ signalling, independently...
Paper Details
Title
All-Optical Analysis of TRPC3/6 Signalling in Mast Cells
Published Date
Feb 1, 2020
Journal
Volume
118
Issue
3
Pages
415a - 415a
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Notes
History