Review paper
Antibody drug conjugates: Development, characterization, and regulatory considerations
Volume: 31, Issue: 6, Pages: 1177 - 1193
Published: Dec 30, 2019
Abstract
Previously, cancer chemotherapy was often accompanied by severe side effects. Antibody drug conjugates (ADCs) were introduced to address this treatment complication. ADCs are a potent category of bioconjugates and immunoconjugates designed as targeted therapy for the treatment of cancer. ADCs are complex molecules composed of an antibody linked via linker chemistry to a cytotoxic payload or drug. Therefore, biologic properties of the...
Paper Details
Title
Antibody drug conjugates: Development, characterization, and regulatory considerations
Published Date
Dec 30, 2019
Volume
31
Issue
6
Pages
1177 - 1193
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