PND96 COMPARISON OF PROPENSITY SCORE METHODS A CASE STUDY OF DIRECT ORAL ANTICOAGULANTS

Propensity Score (PS) methods offer tools to address confounding by indication in comparative effectiveness studies using real world evidence. This work explores the methodological challenges of using these methods to estimate comparative effectiveness for a case study of Direct Oral Anticoagulants (DOACs). PS matching, inverse probability weighting and PS covariate adjustment were explored utilising linked patient-level administrative data,...