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Peter Langhorne
Glasgow Royal Infirmary
Publications 364
Published on Dec 1, 2019in Implementation Science 4.53
Rebecca Fisher13
Estimated H-index: 13
(University of Nottingham),
Niki Chouliara3
Estimated H-index: 3
(University of Nottingham)
+ 9 AuthorsLizz Paley4
Estimated H-index: 4
('KCL': King's College London)
Background Stroke Early Supported Discharge (ESD) is a service innovation that facilitates discharge from hospital and delivery of specialist rehabilitation in patients’ homes. There is currently widespread implementation of ESD services in many countries, driven by robust clinical trial evidence. In England, the type of ESD service patients receive on the ground is variable, and in some regions, ESD is still not offered at all. This protocol presents a study designed to investigate the mechanis...
Published on Jul 26, 2019in Neurology 8.69
Toby B. Cumming23
Estimated H-index: 23
Leonid Churilov33
Estimated H-index: 33
+ 8 AuthorsAmanda G. Thrift57
Estimated H-index: 57
Objective To determine whether early and more frequent mobilization after stroke affects health-related quality of life. Methods A Very Early Rehabilitation Trial (AVERT) was an international, multicenter (56 sites), phase 3 randomized controlled trial, spanning 2006–2015. People were included if they were aged ≥18 years, presented within 24 hours of a first or recurrent stroke (ischemic or hemorrhagic), and satisfied preordained physiologic criteria. Participants were randomized to usual care a...
Published on May 1, 2019in Lancet Neurology 28.75
Rustam Al-Shahi Salman39
Estimated H-index: 39
(Edin.: University of Edinburgh),
David P Minks2
Estimated H-index: 2
+ 937 AuthorsGordon D. Murray4
Estimated H-index: 4
(Edin.: University of Edinburgh)
Summary Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features mo...
Published on May 16, 2019in Stroke 6.05
Julie Bernhardt37
Estimated H-index: 37
(Florey Institute of Neuroscience and Mental Health),
Janice Collier16
Estimated H-index: 16
(Florey Institute of Neuroscience and Mental Health)
+ 2 AuthorsPeter Langhorne65
Estimated H-index: 65
(Glas.: University of Glasgow)
Published on Feb 26, 2019in International Journal of Stroke 4.47
Coralie English19
Estimated H-index: 19
(RMIT: RMIT University),
Mark Bayley38
Estimated H-index: 38
(U of T: University of Toronto)
+ 6 AuthorsBruce C.V. Campbell38
Estimated H-index: 38
(Royal Melbourne Hospital)
Clinical practice guidelines are essential for driving evidence-based clinical care to patients. In an era of ever-increasing research evidence, keeping guidelines up to date is a challenging and resource-intensive process. Advances in technological platforms provide opportunities to develop new models of guideline development that will allow for continuous, rapid updates to recommendations as new evidence emerges. As Australia and other countries begin to develop these models, we have an opport...
Published on May 1, 2019in The Lancet 59.10
Rustam Al-Shahi Salman39
Estimated H-index: 39
Colin Baigent60
Estimated H-index: 60
+ 924 AuthorsJavier Rojas2
Estimated H-index: 2
Summary Background Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on re...
Published on Apr 26, 2019
Amit Kishore4
Estimated H-index: 4
Adam R. Jeans1
Estimated H-index: 1
+ 15 AuthorsXabier Urra26
Estimated H-index: 26
PurposeThe microbiological aetiology of pneumonia complicating stroke is poorly characterised. In this second Pneumonia in Stroke ConsEnsuS statement, we propose a standardised approach to empirica...
Published on May 23, 2019in Cochrane Database of Systematic Reviews 7.75
Alex Pollock22
Estimated H-index: 22
(GCU: Glasgow Caledonian University),
Christine Hazelton6
Estimated H-index: 6
(GCU: Glasgow Caledonian University)
+ 6 AuthorsPauline Campbell8
Estimated H-index: 8
(GCU: Glasgow Caledonian University)
Published on May 1, 2019in Stroke 6.05
Iain McDermid1
Estimated H-index: 1
Mark Barber14
Estimated H-index: 14
(Monklands Hospital)
+ 4 AuthorsTerence J. Quinn27
Estimated H-index: 27
(Glas.: University of Glasgow)
Background and Purpose— Home-time (HT) is a stroke outcome measure based on time spent at home after stroke. We hypothesized that HT assessment would be feasible and valid using national data. Methods— We linked the Scottish Stroke Care Audit to routine healthcare data and calculated 90-day HT for all strokes, 2005 to 2017. We described prognostic validity (Spearman rank correlation) of HT to baseline factors. Results— We were able to calculate HT for 101 969 strokes (99.3% of total Scottish str...
Published on May 1, 2019in BMJ Open 2.38
Apostolos Tsiachristas13
Estimated H-index: 13
(University of Oxford),
Graham Ellis10
Estimated H-index: 10
(Monklands Hospital)
+ 3 AuthorsSasha Shepperd38
Estimated H-index: 38
(University of Oxford)
Objectives To compare the characteristics of populations admitted to hospital-at-home services with the population admitted to hospital and assess the association of these services with healthcare costs and mortality. Design In a retrospective observational cohort study of linked patient level data, we used propensity score matching in combination with regression analysis. Participants Patients aged 65 years and older admitted to hospital-at-home or hospital. Interventions Three geriatrician-led...