Cerebrospinal Fluid Levels of Neurogranin in Parkinsonian Disorders

CSF concentration of neurogranin has been suggested as a biomarker for synapse dysfunction.To investigate CSF neurogranin in parkinsonian disorders compared to controls and Alzheimer's disease and the possible correlations between neurogranin and cognitive and motor impairment.We included 157 patients with PD, 29 with PD with dementia, 11 with dementia with Lewy bodies, 26 with MSA, 21 with PSP, 6 with corticobasal syndrome, 47 controls, and 124...