Original paper
Senescence marker activin A is increased in human diabetic kidney disease: association with kidney function and potential implications for therapy
Volume: 7, Issue: 1, Pages: e000720 - e000720
Published: Dec 1, 2019
Abstract
Objective Activin A, an inflammatory mediator implicated in cellular senescence-induced adipose tissue dysfunction and profibrotic kidney injury, may become a new target for the treatment of diabetic kidney disease (DKD) and chronic kidney diseases. We tested the hypothesis that human DKD-related injury leads to upregulation of activin A in blood and urine and in a human kidney cell model. We further hypothesized that circulating activin A...
Paper Details
Title
Senescence marker activin A is increased in human diabetic kidney disease: association with kidney function and potential implications for therapy
Published Date
Dec 1, 2019
Volume
7
Issue
1
Pages
e000720 - e000720
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Notes
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