Original paper

Somatic mutation signatures in primary liver tumors of workers exposed to ionizing radiation

Volume: 9, Issue: 1
Published: Dec 3, 2019
Abstract
Liver cancer is associated with genetic mutations caused by environmental exposures, including occupational exposure to alpha radiation emitted by plutonium. We used whole exome sequencing (WES) to characterize somatic mutations in 3 histologically distinct primary liver tumors (angiosarcoma of the liver (ASL), cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC)) from Mayak worker subjects occupationally exposed to ionizing radiation...
Paper Details
Title
Somatic mutation signatures in primary liver tumors of workers exposed to ionizing radiation
Published Date
Dec 3, 2019
Volume
9
Issue
1
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