Tetramethylprazine attenuates myocardial ischemia/reperfusion injury through modulation of autophagy
Abstract
The current study aimed to investigate the effects of tetramethylprazine (TMP) on myocardial ischemia/reperfusion (MI/R) injury and its underlying mechanisms. MI/R rat model and hypoxia/reoxygenation (H/R) cardiomyocytes model were established. CK level and LDH activity were detected to evaluate MI/R and H/R injury. Cell viability was determined by cell counting kit-8 (CCK-8) assay. Cell apoptosis were identified by flow cytometry and autophagy...
Paper Details
Title
Tetramethylprazine attenuates myocardial ischemia/reperfusion injury through modulation of autophagy
Published Date
Dec 1, 2019
Journal
Volume
239
Pages
117016 - 117016
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