Fibrin Clot Properties and Thrombin Generation in Hypertrophic Cardiomyopathy

Although most patients with hypertrophic cardiomyopathy (HCM) are oligosymptomatic with normal life expectancy, approximately one-fifth experience increased morbidity and mortality.[1] There are a wide range of clinical manifestations of HCM including diastolic dysfunction, end-stage heart failure (HF), ischemia, left ventricular outflow tract (LVOT) obstruction, atrial fibrillation (AF), syncope, and sudden cardiac death (SCD). Thromboembolic...