Muscle Insulin Resistance in Youth with Obesity and Normoglycemia is Associated with Altered Fat Metabolism

Objective This study aimed to phenotype and compare adipose, hepatic, and muscle insulin sensitivity (IS) in a diet‐ and physical activity–controlled cohort of normoglycemic youth with obesity with that of participants without obesity (controls) to distinguish early metabolic abnormalities in pediatric obesity. Methods Thirty‐eight participants (17 in the control group [BMI < 85th percentile] and 21 youth with obesity [BMI ≥ 95th percentile];...