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Incidence rate and risk factors for radiographic hip osteoarthritis in Japanese men and women: a 10-year follow-up of the ROAD study

Published on Feb 1, 2020in Osteoarthritis and Cartilage4.879
· DOI :10.1016/j.joca.2019.09.006
Toshiko Iidaka4
Estimated H-index: 4
(UTokyo: University of Tokyo),
Shigeyuki Muraki27
Estimated H-index: 27
(UTokyo: University of Tokyo)
+ 6 AuthorsNoriko Yoshimura44
Estimated H-index: 44
(UTokyo: University of Tokyo)
Abstract
Abstract Objective To investigate the incidence and progression rate of radiographic hip osteoarthritis (OA) and its risk factors in Japanese men and women using a large-scale population of a nationwide cohort study, Research on Osteoarthritis/osteoporosis Against Disability (ROAD). Methods From the baseline survey of the ROAD study, 2,975 participants (1,043 men and 1,932 women) aged 23 to 94 years (mean, 70.2 years) living in urban, mountainous, and coastal communities were followed up with hip radiography at 3, 7, and 10 years (mean follow-up, 7.1 years). Radiographs were scored using the Kellgren/Lawrence (K/L) grading system, and radiographic hip OA was defined as K/L ≥2. The incidence and progression rate of hip OA were examined. Acetabular dysplasia was defined as a central-edge angle Results The incidence rate of radiographic hip OA was 5.6/1,000 person-years and 8.4/1,000 person-years in men and women, respectively. The progression rate of hip OA was 2.2/1,000 person-years and 6.0/1,000 person-years in men and women, respectively. The significant risk factors for incident hip OA were age, obesity, and acetabular dysplasia at baseline (hazard risk [HR] 1.05, 95% confidence interval [CI] 1.03-1.08; 1.78, 1.10-2.75; 2.06, 1.30-3.17, respectively). The significant risk factors for progressive hip OA were baseline hip pain and acetabular dysplasia (HR 5.68, 95%CI 1.07-22.61; 14.78, 3.66-56.06, respectively). Conclusion Continued longitudinal surveys of the ROAD study will contribute to knowledge about and potential prevention of incident and progressive hip OA.
  • References (20)
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#1Toshiko Iidaka (UTokyo: University of Tokyo)H-Index: 4
#2Shigeyuki Muraki (UTokyo: University of Tokyo)H-Index: 27
Last. Noriko Yoshimura (UTokyo: University of Tokyo)H-Index: 44
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Summary Objective To investigate radiographic measurements of the hip joint and their associations with hip pain, and the prevalence of acetabular dysplasia defined by radiographic measurements of the hip joint in Japanese men and women using the large-scale population-based cohort of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study. Methods From the baseline survey of the ROAD study (cross-sectional study), 2963 participants (1040 men, 1923 women; mean age, 70.2 years...
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#1Amanda E. Nelson (UNC: University of North Carolina at Chapel Hill)H-Index: 14
#2J L Stiller (UNC: University of North Carolina at Chapel Hill)H-Index: 4
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Summary Objectives We sought to describe the effect of alterations in hip morphology with respect to worsening hip OA in a community-based sample including African American (AA) and white men and women. Methods This nested case–control study defined case hips as Kellgren Lawrence grade (KLG) Results A total of 120 individuals (239 hips; 71 case/168 control) were included (25% male, 26% AA, mean age 62 years, BMI 30 kg/m 2 ). Case hips tended to have greater baseline AP alpha angles, smaller mini...
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#1Toshiko Iidaka (UTokyo: University of Tokyo)H-Index: 4
#2Shigeyuki Muraki (UTokyo: University of Tokyo)H-Index: 27
Last. Noriko Yoshimura (UTokyo: University of Tokyo)H-Index: 44
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Summary Objective Although hip osteoarthritis (OA) is a major cause of hip pain and disability in elderly people, few epidemiologic studies have been performed. We investigated the prevalence of radiographic hip OA and its association with hip pain in Japanese men and women using a large-scale population of a nationwide cohort study, Research on Osteoarthritis/osteoporosis Against Disability (ROAD). Methods From the baseline survey of the ROAD study, 2975 participants (1043 men and 1932 women), ...
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#1Seiya JingushiH-Index: 31
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Background. Osteoarthritis (OA) of the hip is a major disease that affects the healthy lifespan of a population. It is necessary to fully understand the patients’ conditions before a systematic treatment can be applied. However, a nationwide epidemiological study regarding hip OA has not yet been conducted in Japan. The present study examined the current status of patients with hip OA, including the disease etiology. Methods. This is a multiinstitutional study of new patients presenting with hip...
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