P2-236: THE KYNURENINE PATHWAY AND COGNITIVE FUNCTIONING: RESULTS FROM THE MAASTRICHT STUDY

Lieke Bakker; Simone J. P. M. Eussen; Martin P.J. van Boxtel; Miranda T. Schram; Coen D.A. Stehouwer; Carla J.H. van der Kallen; Nicolaas C. Schaper; Pieter C. Dagnelie; Marleen M.J. van Greevenbroek; Anke Wesselius

doi:https://doi.org/10.1016/j.jalz.2019.06.2643

doi.org/10.1016/j.jalz.2019.06.2643

P2-236: THE KYNURENINE PATHWAY AND COGNITIVE FUNCTIONING: RESULTS FROM THE MAASTRICHT STUDY

Lieke Bakker

1

,

Simone J. P. M. Eussen

30

,

..., Anke Wesselius

15

Alzheimer's & Dementia

Volume: 15, Issue: 7S_Part_13

Published: Jul 1, 2019

Abstract

The kynurenine pathway is the main metabolic route of tryptophan degradation. Some kynurenine metabolites, notably quinolinic acid, 3-hydroxykynurenine and kynurenic acid, have been associated with cognitive impairment and neurodegenerative diseases in clinical studies. Yet, little is known whether these associations also exist in the general population. The present study aimed to elucidate the role of the kynurenine pathway as a potential...

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Paper Details

Title

P2-236: THE KYNURENINE PATHWAY AND COGNITIVE FUNCTIONING: RESULTS FROM THE MAASTRICHT STUDY

DOI

doi.org/10.1016/j.jalz.2019.06.2643

Published Date

Jul 1, 2019

Journal

Alzheimer's & Dementia

Volume

15

Issue

7S_Part_13

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