Review paper
CRISPR/Cas9-mediated genome editing in nonhuman primates
Abstract
Owing to their high similarity to humans, non-human primates (NHPs) provide an exceedingly suitable model for the study of human disease. In this Review, we summarize the history of transgenic NHP models and the progress of CRISPR/Cas9-mediated genome editing in NHPs, from the first proof-of-principle green fluorescent protein-expressing monkeys to sophisticated NHP models of human neurodegenerative disease that accurately phenocopy several...
Paper Details
Title
CRISPR/Cas9-mediated genome editing in nonhuman primates
Published Date
Oct 1, 2019
Journal
Volume
12
Issue
10
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Notes
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