An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections
Volume: 26, Issue: 10, Pages: 980 - 987
Published: Sep 30, 2019
Abstract
Nipah virus (NiV) and Hendra virus (HeV) are zoonotic henipaviruses (HNVs) responsible for outbreaks of encephalitis and respiratory illness with fatality rates of 50–100%. No vaccines or licensed therapeutics currently exist to protect humans against NiV or HeV. HNVs enter host cells by fusing the viral and cellular membranes via the concerted action of the attachment (G) and fusion (F) glycoproteins, the main targets of the humoral immune...
Paper Details
Title
An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections
Published Date
Sep 30, 2019
Volume
26
Issue
10
Pages
980 - 987
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