The role of T cell miRNAs for regulatory T cell induction in islet autoimmunity
Abstract
microRNAs (miRNAs) have emerged as critical contributors to immune regulation and homeostasis, and their dysregulation is involved in the aberrant differentiation and function of T cell subsets. In type 1 diabetes (T1D), the clinically overt disease is preceded by a presymptomatic phase which is marked by the presence of islet autoantibodies while the individual is still normoglycemic. Recent analyses revealed impaired regulatory T (Treg) cell...
Paper Details
Title
The role of T cell miRNAs for regulatory T cell induction in islet autoimmunity
Published Date
Sep 1, 2019
Journal
Volume
27
Pages
S122 - S128
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