Single Measurements of Carboxy-Terminal Fibroblast Growth Factor 23 and Clinical Risk Prediction of Adverse Outcomes in CKD

Rationale & Objective An elevated fibroblast growth factor 23 (FGF-23) level is independently associated with adverse outcomes in populations with chronic kidney disease, but it is unknown whether FGF-23 testing can improve clinical risk prediction in individuals. Study Design Prospective cohort study. Setting & Participants Participants in the Chronic Renal Insufficiency Cohort (CRIC) Study (n = 3,789). Exposure Baseline carboxy-terminal FGF-23...