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American Journal of Kidney Diseases
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#1Anoop Sheshadri (UCSF: University of California, San Francisco)H-Index: 2
#2Piyawan Kittiskulnam (Chula: Chulalongkorn University)H-Index: 5
Last. Kirsten L. Johansen (UCSF: University of California, San Francisco)H-Index: 51
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Rationale & Objective Patients receiving dialysis report very low physical activity. We implemented a pilot trial to assess the feasibility of a pedometer-based intervention to gather preliminary evidence about its impact on physical activity, symptoms, and surrogates of cardiovascular risk. Study Design Pilot randomized controlled trial. Setting & Participants 60 dialysis patients from San Francisco dialysis clinics. Intervention Participants were randomly assigned 1:1 to receiving pedometers w...
3 CitationsSource
#1Aaron J. Miller (U of C: University of Chicago)
#2Anthony Chang (U of C: University of Chicago)H-Index: 28
Last. Patrick N. Cunningham (U of C: University of Chicago)H-Index: 20
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Thrombotic microangiopathy (TMA) is an emerging complication of oncologic therapy. Cancer-related causes of renal endothelial cell damage include cytotoxic chemotherapies, radiation given for myeloablation, and direct involvement of renal vasculature by tumor cells. Another class of therapeutic agents that has been implicated in TMA is the vascular endothelial growth factor (VEGF) pathway inhibitors, including the anti-VEGF monoclonal antibody bevacizumab and the VEGF receptor tyrosine kinase in...
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#1Ziyad Al-AlyH-Index: 38
#2Geetha MaddukuriH-Index: 2
Last. Yan XieH-Index: 14
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Proton pump inhibitors (PPIs), long thought to be safe, are associated with a number of nonkidney adverse health outcomes and several untoward kidney outcomes, including hypomagnesemia, acute kidney injury, acute interstitial nephritis, incident chronic kidney disease, kidney disease progression, kidney failure, and increased risk for all-cause mortality and mortality due to chronic kidney disease. PPIs are abundantly prescribed, rarely deprescribed, and frequently purchased over the counter. Th...
1 CitationsSource
#1Alison Thomas (U of T: University of Toronto)H-Index: 1
#2Samuel A. Silver (Queen's University)H-Index: 13
Last. Ron WaldH-Index: 44
view all 17 authors...
Rationale & Objective Surveillance blood work is routinely performed in maintenance hemodialysis (HD) recipients. Although more frequent blood testing may confer better outcomes, there is little evidence to support any particular monitoring interval. Study Design Retrospective population-based cohort study. Setting & Participants All prevalent HD recipients in Ontario, Canada, as of April 1, 2011, and a cohort of incident patients commencing maintenance HD in Ontario, Canada, between April 1, 20...
1 CitationsSource
#1Roman Reindl-Schwaighofer (Medical University of Vienna)H-Index: 7
#2V. MatoussevitchH-Index: 6
Last. Gürkan Sengölge (Medical University of Vienna)H-Index: 5
view all 7 authors...
Rationale & Objective Left-sided internal jugular and all subclavian central venous catheters (CVCs) cause thoracic central vein occlusions (TCVOs) more often than right-sided internal jugular catheters. To enable right-sided CVC placement in patients with TCVO, an inside-out access (IOA) approach was established at 3 vascular access centers in Europe involving use of a novel IOA device advanced from the right femoral vein. In the current analysis, we assessed the eligibility and success rate of...
1 CitationsSource
Abstract The National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) has provided evidence-based guidelines for hemodialysis vascular access since 1996. Since the last update in 2006, there has been a great accumulation of new evidence and sophistication in the guidelines process. The 2019 update to the KDOQI Clinical Practice Guideline for Vascular Access is a comprehensive document intended to assist multidisciplinary practitioners care for chronic kidney disease patien...
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#1Pajaree Krisanapan (CMU: Chiang Mai University)
#2Surachet Vongsanim (CMU: Chiang Mai University)H-Index: 1
Last. Kajohnsak Noppakun (CMU: Chiang Mai University)H-Index: 3
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Rationale & Objective First-line therapy for syndrome of inappropriate antidiuresis (SIAD) is fluid restriction. Additional treatment for patients who do not respond to fluid restriction are water restriction with furosemide or water restriction with furosemide and salt supplementation. However, the efficacy of these treatments has never been tested in a randomized controlled study. The objective of this study was to investigate whether, combined with fluid restriction, furosemide with or withou...
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#1Carl P. Walther (BCM: Baylor College of Medicine)H-Index: 3
#2Vijay Nambi (BCM: Baylor College of Medicine)H-Index: 34
Last. Sankar D. Navaneethan (BCM: Baylor College of Medicine)H-Index: 41
view all 4 authors...
Pulmonary hypertension (PH) is a highly prevalent and important condition in adults with chronic kidney disease (CKD). In this review, we summarize the definition of PH, discuss its pathophysiology and classifications, and describe diagnostic and management strategies in patients with CKD, including those with kidney failure treated by kidney replacement therapy. In the general population, PH is classified into 5 groups based on clinical presentation, pathology, hemodynamics, and management stra...
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Transplantation is the preferred modality of replacement therapy for most patients with kidney failure. In the United States, more than 3,000 new patients are registered each month on the kidney transplant waiting list for this life-saving therapy. A potential kidney transplant recipient’s evaluation typically begins with a referral by the general nephrologist to a transplantation center. In this installment in the Core Curriculum in Nephrology, we endeavor to achieve a shared understanding of t...
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Intensive care medicine
Hemodialysis
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