‘Treatment resistance’ in electroconvulsive therapy (ECT) patients: time to move on

The concept of ‘treatment resistance’ has become all the rage in depression research. It is used to define populations in research studies and in treatment algorithms as a rationale for moving on from standard antidepressants to other therapies. In such algorithms, electroconvulsive therapy (ECT) is often bundled improperly with less effective neurostimulation-methods and experimental pharmacotherapies. We question the utility of the concept of...