Improving therapy of severe infections through drug repurposing of synergistic combinations
Abstract
Infections from multidrug resistant (MDR) pathogens and emerging viruses present challenges for effective clinical treatments. Drug repurposing and combination screens may provide therapies at a fraction of the time and cost of traditional methods of drug development. Synergistic combinations of two or three known compounds can increase therapeutic efficacy and reduce concentrations required for individual drugs, in turn, reducing the risk of...
Paper Details
Title
Improving therapy of severe infections through drug repurposing of synergistic combinations
Published Date
Oct 1, 2019
Volume
48
Pages
92 - 98
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