Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers
Abstract
Our aim was to investigate the patterns and trajectories of white matter (WM) diffusion abnormalities in microtubule-associated protein tau (MAPT) mutations carriers. We studied 22 MAPT mutation carriers (12 asymptomatic, 10 symptomatic) and 20 noncarriers from 8 families, who underwent diffusion tensor imaging (DTI) and a subset (10 asymptomatic, 6 symptomatic MAPT mutation carriers, and 10 noncarriers) were followed annually (median = 4...
Paper Details
Title
Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers
Published Date
Nov 1, 2019
Journal
Volume
83
Pages
54 - 62
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