Original paper
Coagulation factors VII, IX and X are effective antibacterial proteins against drug-resistant Gram-negative bacteria
Abstract
Infections caused by drug-resistant “superbugs” pose an urgent public health threat due to the lack of effective drugs; however, certain mammalian proteins with intrinsic antibacterial activity might be underappreciated. Here, we reveal an antibacterial property against Gram-negative bacteria for factors VII, IX and X, three proteins with well-established roles in initiation of the coagulation cascade. These factors exert antibacterial function...
Paper Details
Title
Coagulation factors VII, IX and X are effective antibacterial proteins against drug-resistant Gram-negative bacteria
Published Date
Aug 9, 2019
Journal
Volume
29
Issue
9
Pages
711 - 724
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Notes
History