Original paper
Systematic evaluation of the mechanisms of zoledronic acid based on network pharmacology
Abstract
Zoledronic acid (ZA) is an FDA-approved drug and a third-generation bisphosphonate (BPs). A systematic evaluation of the mechanisms of ZA has not previously been performed. In this study, validated targets of ZA were screened using PubChem, Herbal Ingredients’ Targets Database (HIT), Binding Database (BindingDB), and ChemBank, and potential targets of ZA were identified based on structural characteristics of ligands and proteins. The candidate...
Paper Details
Title
Systematic evaluation of the mechanisms of zoledronic acid based on network pharmacology
Published Date
Dec 1, 2019
Volume
83
Pages
107097 - 107097
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Notes
History