Brazilian propolis extract reduces intestinal barrier defects and inflammation in a colitic mouse model
Abstract
Brazilian propolis is rich in cinnamic acid derivatives and reportedly reduces intestinal inflammation in rodents; however, the underlying mechanisms remain unclear. We hypothesized that the regulation of tight junction (TJ) barrier, Th17 cell differentiation, and/or, macrophage activation by cinnamic acid derivatives were involved in the propolis-mediated anti-inflammatory effect. Mice were orally administered 2% dextran sodium sulfate (DSS) in...
Paper Details
Title
Brazilian propolis extract reduces intestinal barrier defects and inflammation in a colitic mouse model
Published Date
Sep 1, 2019
Journal
Volume
69
Pages
30 - 41
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