Calcium: A New Guardian of Naive Pluripotency
Abstract
In this issue of Cell Stem Cell, MacDougall et al. (2019) utilized a CRISPR mutagenesis screen to identify factors for mESC self-renewal and found that intracellular calcium and nuclear export act in naive pluripotency exit. Combined knockout of Tcf7l1 and the calcium transporter Atp2b1 enabled mESCs to self-renew in the absence of LIF and...
Paper Details
Title
Calcium: A New Guardian of Naive Pluripotency
Published Date
Aug 1, 2019
Journal
Volume
25
Issue
2
Pages
169 - 170
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Notes
History