Original paper
Cross-Communication Between Histone Acetyltransferase And Histone Deacetylase Epigenetic Enzymes Augments Oxidative Stress And Fibrosis In The Kidney Of Diabetic Mice
Abstract
Background and Aims: Accumulating evidence implicates histone acetylation-based epigenetic mechanisms in the pathoetiology of diabetes-associated micro-/macrovascular complications. Diabetic nephropathy is a progressive chronic inflammatory microvascular disorder affecting the glomerular capillaries, a condition that ultimately impairs kidney function. Hitherto, the involvement of histone acetyltransferase (HAT) and histone deacetylase (HDAC)...
Paper Details
Title
Cross-Communication Between Histone Acetyltransferase And Histone Deacetylase Epigenetic Enzymes Augments Oxidative Stress And Fibrosis In The Kidney Of Diabetic Mice
Published Date
Aug 1, 2019
Journal
Volume
287
Pages
e26 - e26
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Notes
History