Original paper
Characterization of Kcnk3 -Mutated Rat, a Novel Model of Pulmonary Hypertension
Abstract
Rationale: Pulmonary arterial hypertension is a severe lethal cardiopulmonary disease. Loss of function mutations in KCNK3 (potassium channel subfamily K member 3) gene, which encodes an outward rectifier K + channel, have been identified in pulmonary arterial hypertension patients. Objective: We have demonstrated that KCNK3 dysfunction is common to heritable and nonheritable pulmonary arterial hypertension and to experimental pulmonary...
Paper Details
Title
Characterization of Kcnk3 -Mutated Rat, a Novel Model of Pulmonary Hypertension
Published Date
Sep 13, 2019
Journal
Volume
125
Issue
7
Pages
678 - 695
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Notes
History