Circulation Research
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#1Nirav Dhanesha (Roy J. and Lucille A. Carver College of Medicine)H-Index: 13
#2Manish Jain (Roy J. and Lucille A. Carver College of Medicine)
Last. Shigeyuki Kon (Fukuyama University)H-Index: 31
view all 11 authors...
#1Nadine Suffee (French Institute of Health and Medical Research)H-Index: 1
#2Thomas Moore-MorrisH-Index: 12
Last. Michel Pucéat (French Institute of Health and Medical Research)H-Index: 43
view all 11 authors...
Rationale: Fibro-fatty infiltration of sub-epicardial layers of the atrial wall has been shown to contribute to the substrate of atrial fibrillation (AF). Objective: Here, we examined if the epicar...
#1raj nayan Sewduth (Katholieke Universiteit Leuven)H-Index: 2
Last. Francis Impens (UGent: Ghent University)H-Index: 23
view all 11 authors...
Rationale: Noonan syndrome (NS) is one of the most frequent genetic disorders. Bleeding problems are among the most common, yet poorly defined complications associated with NS. A lack of consensus on the management of bleeding complications in NS patients indicates an urgent need for new therapeutic approaches. Objective: Bleeding disorders have recently been described in NS patients harboring mutations of LZTR1, an adaptor for CULLIN3 ubiquitin ligase complex. Here, we assessed the pathobiology...
#1Jee Myung Yang (KAIST)H-Index: 4
#2Chan Soon Park (KAIST)H-Index: 1
Last. Hyun Ho Jung (Chonnam National University)H-Index: 4
view all 23 authors...
Rationale: Central nervous system (CNS) has low vascular permeability by organizing tight junction (TJ) and limiting endothelial transcytosis. While TJ has long been considered to be responsible fo...
#1Liang Xiao (VUMC: Vanderbilt University Medical Center)H-Index: 15
#2Luciana Simao do Carmo (VUMC: Vanderbilt University Medical Center)H-Index: 1
Last. G HarrisonDavid (VUMC: Vanderbilt University Medical Center)H-Index: 123
view all 5 authors...
Rationale: Effector memory T lymphocytes (TEM cells) exacerbate hypertension in response to repeated hypertensive stimuli. These cells reside in the bone marrow for prolonged periods and can be rea...
1 CitationsSource
#1Karsten Müller (MPG: Max Planck Society)H-Index: 38
#2Friederike ThielH-Index: 1
Last. Gerhard SchulerH-Index: 100
view all 12 authors...
Rationale: Heart failure (HF) following heart damage leads to a decreased blood flow due to a reduced pump efficiency of the heart muscle. A consequence can be insufficient oxygen supply to the org...
1 CitationsSource
#1Alan J. Mouton (UMMC: University of Mississippi Medical Center)H-Index: 6
#2Xuan Li (UMMC: University of Mississippi Medical Center)
Last. John E. Hall (UMMC: University of Mississippi Medical Center)H-Index: 65
view all 4 authors...
Obesity and hypertension, which often coexist, are major risk factors for heart failure and are characterized by chronic, low-grade inflammation, which promotes adverse cardiac remodeling. While macrophages play a key role in cardiac remodeling, dysregulation of macrophage polarization between the proinflammatory M1 and anti-inflammatory M2 phenotypes promotes excessive inflammation and cardiac injury. Metabolic shifting between glycolysis and mitochondrial oxidative phosphorylation has been imp...
#1Caroline G. Shimoura (University of North Texas Health Science Center)
#2Keisa W. Mathis (University of North Texas Health Science Center)H-Index: 9
#1Edoardo BerteroH-Index: 6
#2Brian O'Rourke (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 74
Last. Christoph MaackH-Index: 31
view all 3 authors...
#1Yvonne Döring (LMU: Ludwig Maximilian University of Munich)H-Index: 23
#1Yvonne Döring (University of Bern)
Last. Emiel van van der Vorst (LMU: Ludwig Maximilian University of Munich)
view all 9 authors...
Top fields of study
Diabetes mellitus
Cell biology