Isoallopregnanolone reduces tic‐like behaviours in the D1CT‐7 mouse model of Tourette syndrome

Tourette syndrome ( TS ) is a neuropsychiatric disorder characterised by multiple, persistent tics. These semi‐voluntary motor and phonic manifestations are typically aggravated by exposure to acute stress, yet the mechanisms underlying this exacerbation remain unclear. Using a well‐characterised animal model of TS , the D1 CT ‐7 mouse, we recently showed that acute stress increases tic‐like responses and causes sensorimotor gating deficits, as...