Platelets as Potent Signaling Entities in Type 2 Diabetes Mellitus

T2DM has a multifactorial nature, and systemic inflammation, endothelial dysfunction, with resulting hypercoagulation and platelet dysfunction, are key disease elements. Increased circulating inflammatory markers are present in T2DM, and they originate from various sources, including the platelets themselves. Platelets have important cellular crosstalk functions in T2DM, and they become proinflammatory entities, driving inflammation in this...