Frequency-dependent exacerbation of Alzheimer’s disease neuropathophysiology
Abstract
Neuronal activity patterns are disrupted in neurodegenerative disorders, including Alzheimer’s disease (AD). One example is disruption of corticothalamic slow oscillations responsible for sleep-dependent memory consolidation. Slow waves are periodic oscillations in neuronal activity occurring at frequencies of <1 Hz. The power, but not the frequency of slow oscillations is altered in a mouse model of AD. Optogenetic rescue of slow...
Paper Details
Title
Frequency-dependent exacerbation of Alzheimer’s disease neuropathophysiology
Published Date
Jun 20, 2019
Journal
Volume
9
Issue
1
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