Original paper
Liver infiltrating T cells regulate bile acid metabolism in experimental cholangitis
Abstract
•Antigen-specific CD8+ T cells can control bile acid metabolism in a murine model of cholangitis. •The effect of T cells on bile acid metabolism partly depends on TNF and IFN-γ, and on T cell contact with hepatocytes. •Understanding the effect of lymphocytes on bile acid metabolism may help in the design of combined treatment strategies. Background & Aims T cells are central mediators of liver inflammation and represent potential treatment...
Paper Details
Title
Liver infiltrating T cells regulate bile acid metabolism in experimental cholangitis
Published Date
Oct 1, 2019
Journal
Volume
71
Issue
4
Pages
783 - 792
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Notes
History