Original paper

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice

Volume: 8, Issue: 1
Published: Apr 12, 2018
Abstract
Mutations in mitochondrial DNA (mtDNA) lead to heteroplasmy, i.e., the intracellular coexistence of wild-type and mutant mtDNA strands, which impact a wide spectrum of diseases but also physiological processes, including endurance exercise performance in athletes. However, the phenotypic consequences of limited levels of naturally arising heteroplasmy have not been experimentally studied to date. We hence generated a conplastic mouse strain...
Paper Details
Title
Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice
Published Date
Apr 12, 2018
Volume
8
Issue
1
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.