Therapeutic drug monitoring with biologic agents in immune mediated inflammatory diseases

Introduction: Biologic therapy has revolutionized the treatment of immune mediated inflammatory diseases (IMID), such as inflammatory bowel disease (IBD), rheumatoid and psoriatic arthritis, ankylosing spondylitis and psoriasis. Nevertheless, some patients exhibit primary nonresponse (PNR) or secondary loss of response (SLR) to biologics.Areas covered: This collaborative review provides data on the role of therapeutic drug monitoring (TDM) in...