Targeted genetic analysis of cerebral blood flow imaging phenotypes implicates the INPP5D gene
Abstract
The vascular hypothesis of Alzheimer's disease (AD) has proposed the involvement of brain hypoperfusion in AD pathogenesis, where cognitive decline and dysfunction result from dwindling cerebral blood flow (CBF). Based on the vascular hypothesis of Alzheimer's disease, we focused on exploring how genetic factors influence AD pathogenesis via the cerebrovascular system. To investigate the role of CBF endophenotypes in AD pathogenesis, we...
Paper Details
Title
Targeted genetic analysis of cerebral blood flow imaging phenotypes implicates the INPP5D gene
Published Date
Sep 1, 2019
Journal
Volume
81
Pages
213 - 221
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