Original paper
Integrated modeling of a continuous direct compression tablet manufacturing process: A production scale case study
Abstract
A flowsheet model for a continuous direct compression tableting process is developed and applied to process data generated at production scale. The model contains powder feeding, blending and tablet compaction unit operations. The dataset was provided by Merck & Co., Inc., Kenilworth, NJ USA using a GEA ConsiGma™ continuous direct compression process designed for approximately 50 kg/h throughput using a six ingredient, potentially commercial,...
Paper Details
Title
Integrated modeling of a continuous direct compression tablet manufacturing process: A production scale case study
Published Date
Sep 1, 2019
Journal
Volume
354
Pages
199 - 210
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Notes
History