Original paper

Downregulation of microRNA‐155 stimulates sevoflurane‐mediated cardioprotection against myocardial ischemia/reperfusion injury by binding to SIRT1 in mice

Volume: 120, Issue: 9, Pages: 15494 - 15505
Published: May 17, 2019
Abstract
The inhaled sevoflurane has been demonstrated to protect against myocardial ischemia/reperfusion (I/R) injury. However, the relative mechanisms of sevoflurane-mediated cardioprotection remain largely unknown. This study intends to explore the effect of miR-155 on the sevoflurane-mediated cardioprotection by regulating Sirtuin 1 (SIRT1) in mouse models of myocardial I/R.Left anterior descending coronary artery ligation was used to induce models...
Paper Details
Title
Downregulation of microRNA‐155 stimulates sevoflurane‐mediated cardioprotection against myocardial ischemia/reperfusion injury by binding to SIRT1 in mice
Published Date
May 17, 2019
Volume
120
Issue
9
Pages
15494 - 15505
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