Original paper
Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study
Abstract
Animal studies indicate that the kappa-opioid receptor/dynorphin system plays an important role in cocaine binges and stress-induced relapse. Our goal was to investigate changes in kappa-opioid receptor (KOR) availability in the human brain using positron emission tomography (PET), before and after a cocaine binge. We also investigated the correlation between KOR and stress-induced cocaine self-administration. PET imaging was performed with the...
Paper Details
Title
Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study
Published Date
Apr 26, 2019
Journal
Volume
44
Issue
10
Pages
1720 - 1727
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Notes
History