Cross sex hormone treatment is linked with a reversal of cerebral patterns associated with gender dysphoria to the baseline of cisgender controls

Transgender persons experience incongruence between their gender identity and birth‐assigned sex. The resulting gender dysphoria (GD), is frequently treated with cross‐sex hormones. However, very little is known about how this treatment affects the brain of individuals with GD, nor do we know the neurobiology of GD. We recently suggested that disconnection of fronto‐parietal networks involved in own‐body self‐referential processing could be a...