Original paper
DNA-encoded bispecific T cell engagers and antibodies present long-term antitumor activity
Abstract
Specific antibody therapy, including mAbs and bispecific T cell engagers (BiTEs), are important new tools for cancer immunotherapy. However, these approaches are slow to develop and may be limited in their production, thus restricting the patients who can access these treatments. BiTEs exhibit a particularly short half-life and difficult production. The development of an approach allowing simplified development, delivery, and in vivo production...
Paper Details
Title
DNA-encoded bispecific T cell engagers and antibodies present long-term antitumor activity
Published Date
Apr 18, 2019
Journal
Volume
4
Issue
8
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Notes
History