18F-Flortaucipir in TDP-43 associated frontotemporal dementia
Abstract
Retention of 18 F-Flortaucipir is reportedly increased in the semantic variant of primary progressive aphasia (svPPA), which is dominated by TDP-43 pathology. However, it is unclear if 18 F-Flortaucipir is also increased in other TDP-43 diseases, such as bvFTD caused by a C9orf72 gene mutation. We therefore recruited six C9orf72 expansion carriers, six svPPA patients, and 54 healthy controls. All underwent 18 F-Flortaucipir PET and MRI scanning....
Paper Details
Title
18F-Flortaucipir in TDP-43 associated frontotemporal dementia
Published Date
Apr 15, 2019
Journal
Volume
9
Issue
1
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