Should familial disease be considered as a negative prognostic factor in micropapillary thyroid carcinoma?

An increased aggressiveness of familial papillary thyroid carcinoma (FPTC) compared with sporadic form has been reported. On the contrary, the biological behavior of familial microPTC (FmPTC) is still debated. To assess if familial diseases should be considered as a negative prognostic factor in mPTC, the clinical presentation and outcome of FmPTC and sporadic mPTC (SmPTC) were compared. We retrospectively analyzed 291 mPTC (SmPTC n = 248, FmPTC...